Cullen's sign may be accompanied by Grey-Turner's sign (bruising of the flank). Grey Turner sign refers to bruising of the flanks and may occur in conjunction with Cullen sign, especially in patients with retroperitoneal hemorrhage 6) Figure 1: (A) Periumbilical ecchymosis (Cullen sign) and (B) connecting patchesof ecchymosis on the left flank (Grey Turner sign) in a 47-year-old man withsudden onset of left-flank pain Cullen sign and Grey Turner sign, named after Thomas Stephen Cullen, MB, and George Grey Turner, MBBS, respectively, are signs of abdominal wall hemorrhage and are generally associated with acute pancreatitis. However, the research from which these signs arose was documented long before Cullen and Grey Turner made their contributions Cullen sign and Grey Turner sign are most frequently associated with hemorrhagic pancreatitis, are seen in 1% to 2% of cases, and typically are seen 2 to 3 days after onset. These signs may also be seen in ruptured ectopic pregnancy, severe trauma, leaking or ruptured abdominal aortic aneurysm, coagulopathy, or any other condition associated.
Grey Turner's sign, bruising of the flanks, is an important clue that the source of the injury may be inside the body. The most common cause of Grey Turner's sign is abdominal hemorrhage (bleeding. Cullen's sign and Grey Turner's signs, described as ecchymosis about periumbilical area and in one or both flanks respectively, represent the extravasation of hemorrhagic pancreatic exudate to these areas. 1,2 They occur in < 1% of individuals with acute pancreatitis and are associated with high mortality Grey Turner's sign takes 24-48 hours to develop, and can predict a severe attack of acute pancreatitis. Grey Turner's sign may be accompanied by Cullen's sign. Both signs may be indicative of pancreatic necrosis with retroperitoneal or intra-abdominal bleeding. Grey Turner's sign is named after British surgeon George Grey Turner Grey Turner's sign is an uncommon subcutaneous manifestation of intra-abdominal pathology that manifests as ecchymosis or discoloration of the flanks. Classically it correlates with severe acute necrotizing pancreatitis, often in association with Cullen's sign (periumbilical ecchymosis). It may also
Cullen TS. Bluish discolouration of the umbilicus as a diagnostic sign when ruptured extrauterine pregnancy exists. In: Contributions to Medical and Biological Research. 1919; 1: 420-422 ; Chung KM, Chuang SS. Cullen and Grey Turner signs in idiopathic perirenal hemorrhage. CMAJ. 2011 Nov 8;183(16):E1221; Harris S, Naina HV. Cullen's sign. Cullen's sign is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus.. It is named for gynecologist Thomas Stephen Cullen (1869-1953), who first described the sign in ruptured ectopic pregnancy in 1916.. This sign takes 24-48 hours to appear and can predict acute pancreatitis, with mortality rising from 8-10% to 40%.It may be accompanied by Grey Turner's. Join Us https://www.youtube.com/channel/UC2PgM2cakYLh_m90pctX5xA/joinThis video educates about Fox Sign, Grey turner sign in flanks, cullen sign in around um.. Description. Grey Turner sign: atraumatic abdominal ecchymosis, in particular - bruising of the flanks.George Grey Turner reported a 'dirty-green' discolouration on both loins of a patient with acute pancreatitis (confirmed on operation) Incidence of 3-5% in patients with acute pancreatitis, associated with increased mortality (30-40%) and increased risk of pseudocyst formation
1. Chung KM, Chuang SS. Cullen and Grey Turner signs in idiopathic perirenal hemorrhage. Canadian Med Assoc J. 2011;183:16. 2.Wright W. Cullen sign and Grey Turner sign revisited. J Am Osteopathic Assoc2016;116:398-401. How to cite this article: Wong E, Sayed-Hassen A. Grey Turner's sign in severe acute pancreatitis. Clin Case Rep. 2021;9. Cullen sign is clinically viewed as a marker of serious health problems. CausesCauses include: • acute pancreatitis• bleeding from blunt abdominal trauma• bl.. Ecchymoses in the periumbilical region (Cullen's sign) (Panel A) and flank (Turner's sign) (Panel B) were noted. Computed tomographic scanning confirmed a retroperitoneal hemorrhage. In 1918,.. Grey Turner's sign, Cullen's sign and Fox's sign can be rarely observed in severe acute pancreatitis  ( Fig. 17 ). [posterng.netkey.at] Two physical examination signs of acute pancreatitis include Cullen's sign and Grey Turner's sign
Grey Turner's sign is an uncommon subcutaneous manifestation of intra-abdominal pathology that manifests as ecchymosis or discoloration of the flanks. Classically it correlates with severe acute necrotizing pancreatitis, often in association with Cullen's sign (periumbilical ecchymosis) Grey-Turner sign can be accompanied by another sign, the Cullen sign; also of similar pathophysiologic basis but at a different location. Grey-Turner refers to bruising at the flank; Cullen sign refers to bruising at the periumbilical region. Grey-Turner vs Cullen: How to remember which is which? The way I remember which is Grey-Turner and. Grey Turner's sign and/or Cullen's sign, or a bluish discoloration to the flanks and umbilicus, may also be noted and are indicative of severe hemorrhagic pancreatitis, while [physio-pedia.com] In severe cases, flank ecchymosis ( Grey - Turner sign ) or periumbilical ecchymosis (Cullen's sign) may be seen Cullen's sign and Grey-Turner's sign. Bonani M(1), Franzen D, Anabitarte P. Author information: (1)Department of Internal Medicine, Hospital of Zollikerberg, Zollikerberg, Switzerland
The Cullen sign, a bluish discoloration of the periumbilical skin, was originally described in 1918 by the gynecologist Thomas Cullen, MD, in a patient with a ruptured ectopic pregnancy. The Grey Turner sign, an ecchymotic discoloration of the lateral abdominal wall or flank, was first reported in 1920 by a surgeon, Dr. George Grey Turner, in a. First identified by Dr. Thomas Stephen Cullen (1868—1953) in 1918, this condition often coexists with Grey Turner's sign, a bruising of the abdominal walls or flanks. While occurrence is relatively rare—it's seen in less than 1% of ectopic pregnancies, and in 1-3% of pancreatitis patients —Cullen sign is clinically viewed as a. Coexistence of Cullen's and Grey Turner's signs in acute pancreatitis. Bosmann M(1), Schreiner O, Galle PR. Author information: (1)First Department of Medicine, University of Mainz, Germany. firstname.lastname@example.org Comment in Am J Med. 2009 Nov;122(11):e15; author reply e17. PMID: 19332225. Cullen's sign (as opposed to Grey Turner's sign which refers to bruising of the flanks). Yassar Alamri, Steven Soule, Gary Lim New Zealand Medical Journal 2013 December 13, 126 (1387): 184-6 Stabler's sign revisited in a spontaneously ruptured neuroblastoma of the newborn
And there are 2 signs of pancreatitis you need to be aware of, because nursing schools love to test you one these: Cullen's sign; Grey Turner's sign; Cullen's sign is bruising around the belly button. And Grey Turner's (or just Turner's) sign is bruising on the patients sides, the flank area The Grey-Turner sign alone and the Cullen sign alone occurred in one patient each. Two patients had both of these signs and the fifth patient displayed Cullen's, Grey-Turner's and Fox's signs. Four of the five patients were women older than 70 years and had a biliary cause of their disease
The presence of Cullen's sign and Grey-Turner's sign are suggestive of retroperitoneal haemorrhage. Cullen's sign occurs due to tracking of blood along the gastrohepatic and falciform ligaments into the umbilical area. Look For; Bluish discolouration / bruising around the umbilicus Compare and contrast Cullens sign and Grey Turners sign What is the from HEALTH ASS NR304 at Chamberlain College of Nursin Grey-Turner's sign and Cullen's sign can be easily confused with one another because they are both characterized by the same physical findings in different locations. Grey-Turner's sign is located on the flanks. Cullen's sign is located around the umbilicus (periumbilical). These signs can be seen when bleeding occurs inside the abdomen. 3 different cases of Grey-Turner's and Cullen's sign in patients with liver cancer. They all had extensive portal vein thrombosis and died within hours or days. These bruises are usually associated with retroperitoneal hemorrhage in acute pancreatitis. I presume in these patients the mechanism was portal vein rupture
Cullen's and Grey-Turner's signs have been described with intra-abdominal haemorrhage most commonly associated with pancreatitis. Rare associations include ectopic pregnancy, malignant disease (liver, abdominal metastasis), perforated duodenal ulcer, liver abscess, and splenic rupture British surgeon George Grey Turner described Grey Turner's sign in 1920 1 in acute pancreatitis. This sign is frequently associated with retroperitoneal bleed due to acute pancreatitis, ruptured aortic aneurysm and ruptured ectopic pregnancy. There are reported cases of this sign due to ruptured hepatocellular carcinoma 2 and perirenal. Tachycardia is a less helpful sign, as the adrenergic response can be driven by pain and stress. Cullen's and Grey Turner's sign Cullen's sign (peri-umbilical bruising) and Grey-Turner's sign (flank bruising) are important to be aware of, but these are late signs o f severe intra-abdominal and retroperitoneal haemorrhage, respectively A 34-year old man with alcoholic cirrhosis and portal hypertension, presented with abdominal distension and pain of 2 weeks' duration. Examination showed Cullen's sign (periumbilical ecchymosis; figure A), Grey-Turner's sign (ecchymosis on the abdominal flank; figure B) and ascites. A working diagnosis of acute pancreatitis seemed reasonable because both Cullen's and Grey-Turner's signs are. Cullen's sign and Grey-Turner's sign on MedShr. Developed by doctors, MedShr is the secure and easy way to discuss vascular surgery cases with verified medical colleagues
Cullen and Grey Turner signs in abdominal pain. A 46‐year‐old man with a history of chronic hepatitis B and alcohol misuse presented with acute abdominal pain. On physical examination, in addition to jaundice and severe pallor, he had massive ascites and ecchymoses over the periumbilical area, compatible with Cullen sign (Figure, A), and. Hello! My name is Jen, I am a PA in the Emergency Department. I came across your diagram of Cullen's sign and Grey Turner sign, which is a great tool to help remember which is which! The way the information is presented however almost makes it sound like this is a common finding of acute pancreatitis when you say (appears in 1-2 days) Picture 8: Battle sign or mastoid ecchymosis due to basilar skull fracture Source: Alamy. Picture 9: Illustration of Cullen sign (periumbilical ecchymosis) and Grey Turner sign (ecchymosis on the lateral abdominal wall) Source: Anesthesia Key. Picture 10: Petechiae vs. ecchymosis vs. hematoma Source: StudyBlu Rectus sheath haematoma presenting with Cullen's sign and Grey-Turner's sign. C M Guthrie, H A Stanfey Scottish Medical Journal 1996, 41 (2): 54-5 The incidence and prognosis of body wall ecchymosis in acute pancreatitis
Cullen Sign and Grey Turner Sign Revisited Published in: Journal of Osteopathic Medicine, June 2016 DOI: 10.7556/jaoa.2016.081: Pubmed ID: 27214777. Authors: William F. Wright View on publisher site Alert me about new mentions. Twitter Demographics Cullen's sign occurs due to tracking of haemorrhagic fluid from the retro-peritoneum along the gastrohepatic and falciform ligament to the umbilicus. 3 In contrast Grey Turner's sign is due to the diffusion of blood from the posterior pararenal space to the lateral edge of the quadratus lumborum muscle, where a defect in the transversalis. Grey Turner's sign is a well described butrarely seen sign usually indicating severe intra-abdominal pathology. Classically it is associated with severe acute pancreatitis but can beassociated with a number of other severe intra-abdominal conditions Grey Turner's sign is identified by finding bruises located on the lower abdomen. A Grey Turner's sign develops when blood, typically from the internal organs, escapes from the blood vessels and travels into the layers of tissue located directly under the skin. The proximity of this blood to the surface of the body allows it to be visible to the naked eye Properitoneal fat. The properitoneal fat, also known as the preperitoneal space, is a fat containing space in the abdomen. Posteriorly it lies deep to the transversalis fascia, and fills the posterior pararenal space. Laterally it thickens and forms the properitoneal fat pad, which is the anterior extension of posterior pararenal space
. Clinically, these signs represent an ecchymotic discoloration, a superficial edema with bruising in the subcutaneous fatty tissue, located in the periumbilical region (Cullen's sign) or along the flanks (Grey-Turner's sign) [ 58 ] Cullen's sign (peri-umbilical ecchymoses) indicates intraperitoneal rupture of the haematoma and Grey-Turner's sign (flank discolouration) is probably secondary to extra-peritoneal extension of the haematoma
Battle's sign Cullen sign Grey-Turner sign Kehr Sign Raccoon eye sign posting requires one reference from an English titled, peer-reviewed nursing journal less than five years old. The article for the initial posting must be different than the article for the response to peer posting. The initial posting also requires a reference from the. In acute pancreatitis, Cullen's or Turner's sign occurs in. approximately 3 percent of patients and is associated with. a mortality of 37 percent. Although most commonly. described in hemorrhagic pancreatitis, neither of these. signs is specific to this condition. Cullen's sign arises from the spread of retroperitoneal The bruising appears as a blue discoloration, and is a sign of retroperitoneal hemorrhage, or bleeding behind the peritoneum, which is a lining of the abdominal cavity. Grey Turner's sign takes 24-48 hours to develop, and can predict a severe attack of acute pancreatitis. Grey Turner's sign may be accompanied by Cullen's sign
5. Describe how the nurse would evaluate signs associated with physical trauma: Battle's sign Cullen sign Grey-Turner sign Kehr Sign Raccoon eye sign posting requires one reference from an English titled, peer-reviewed nursing journal less than five years old. The article for the initial posting must be different than the article for the response [ subcutaneous tissue. With Cullen's sign, blood diffuses from the retroperitoneum along the gastrohepatic and falciform ligaments to the umbilicus. With Grey Turner's sign, blood diffuses from the posterior pararenal space to the lateral edge of the quadratus lumborum muscle.[1-3] These signs may be found in 1-3% of all cases of acute.
Subcutaneous manifestations (Grey Turner's sign and Cullen's sign) of severe acute pancreatitis (SAP) are often discussed but rarely observed in a daily clinic setting. This paper will demonstrate the anatomic pathways followed by the extravasated pancreatic enzymes and how their effects lead to these ecchymoses by multiplanar reformation (MPR. Also, blood from a retroperitoneal hemorrhage might shift and collect at the inguinal ligament (Fox's sign) or the scrotum (Bryant's sign).</P>After the onset of pancreatitis, the time to the appearance of either Grey Turner's or Cullen's signs averages 3 days. 3 The relevance of a direct action of pancreatic digestive enzymes on the soft. . Local areas of discoloration (bruising) and induration of the skin about the umbilicus and in the region of the loins due to extravasation of blood. It is a clinical sign seen after 2-3 days in acute haemorrhagic pancreatitis and other causes of retroperitoneal haemorrhage. Turner-Cullen symptom is entered as Cullen's. Cullen's sign: [ kul´enz ] bluish discoloration around the umbilicus sometimes occurring in intraperitoneal hemorrhage, especially following rupture of the fallopian tube in ectopic pregnancy. A similar discoloration is seen in acute hemorrhagic pancreatitis Signs and symptoms include: • ALOC • Dyspnoea • Abdominal pain/discomfort, guarding and tenderness on palpation • Hypovolaemic shock • Abdominal bruising (e.g. Cullen's sign, Grey Turner sign) and distension can be a late sign and difficult to determine. • Shoulder tip pain (Kehr's sign
SYMPTOMS • Pain or tenderness • A rapid heart rate • Rapid breathing • Sweating • Cold, clammy, pale or bluish skin • Confusion or low level of alertness • Blunt trauma may cause bruising. • Cullen's sign • Grey turner's sign • Kehr's sign 22 Grey Turner's sign () Concepts: Finding (T033) SnomedCT: 62988009: English: Abdom wall discolor, L flank, Abdom wall discolour, L flank, Gray Turner's sign, flank ecchymosis, Grey Turner's sign (physical finding), abdomen Grey Turner's sign (flank ecchymosis), ecchymosis of flank (physical finding), ecchymosis of flank, Grey Turner sign, gray turner's sign, grey sign turner, grey sign turners. Skin signs in acute pancreatitis are well-known and frequently discussed manifestations accompanied by unfavorable prognoses although they may rarely appear in clinical and forensic medicine. In 2018, the district attorney's office ordered a forensic autopsy for a 74-year-old man with terminal stage pancreatic cancer. The autopsy was ordered based on accusations of the deceased's widow.
Strikingly, at a very early stage of subcortical processing (the vestibular nuclei) the neuronal response in rhesus monkeys is suppressed when they actively move their head relative to their body (Brooks JX and Cullen KE, 2019) (Cullen KE and Minor LB, 2002;Jamali M et al., 2009;Sadeghi SG et al., 2007) Help | Sign in. Royal Hospital School . WORCESTERSHIRE COUNTY LEAGUE | Division Two 1st XI. 28 MAY 2011 @ 13:30 | Regency Road | 6pts. MONMOUTH CC. WON BY 3 WICKETS. 20pts . Malvern CC. 1st XI 181 / 9 (50) Monmouth CC. 1st XI 182 / 7 (44) Won the toss and elected to field. Malvern CC. THE CULLEN AND GREY TURNER SIGNS The Cullen sign, a bluish discoloration of the periumbil- ical skin, was originally described in 1918 by the gyne-cologist Thomas Cullen, MD, in a patient with a rup-tured ectopic pregnancy.1 The Grey Turner sign, an ec-chymotic discoloration of the lateral abdominal wall o . She said Turner's sign is from retroperitoneal haemorrhage with hemorrhagic pancreatitis, but wasn't sure about Cullen's sign since that probably couldn't be retroperitoneal (since its periumbilical) Cullen's sign (ecchymosis of the periumbilical region) and Grey Turner's sign (ecchymosis of the flank) suggests retroperitoneal hemorrhage associated with severe pancreatic necrosis and high mortality. Early recognition of these physical examination findings can hel
The findings demonstrate a variation of Cullen's and Grey Turner's sign, most often found in patients with hemorrhagic pancreatitis. An abdominal radiograph revealed a ground glass appearance with radiolucency outlining the bladder, consistent with retroperitoneal air. The chest radiograph showed mediastinal air extending into the neck Bruising around the umbilicus (belly button) is referred to as Cullen's sign, and suggests internal bleeding in the abdomen. Bruising on the flanks (between the rib cage and hips on the side of the abdomen) is known as Grey Turner's sign and also suggest bleeding in the abdomen or retroperitoneal space (cavity towards the back of the abdomen. Two signs associated are Gray-Turner's signs and Cullen's sign. Gray-Turner's is indicative of retroperitoneal hemorrhage. It presents with bruising of the flanks and takes 24 hours to develop. Cullen's signs also take 24 hours to appear and are characterized by an ecchymotic region around the umbilicus that has an irregular border Cullen's sign (bluish skin around the belly button) Grey-Turner sign (reddish-brown skin discoloration along the flanks) Erythematous skin nodules; Chronic Pancreatitis Symptoms and Signs. Pain is less common in chronic pancreatitis than in acute pancreatitis. Some people with chronic pancreatitis have pain, but many people do not experience. Cullen's sign (bluish discoloration of umbilicus) Chronic hemorrhagic pancreatitis: Grey-Turner's sign (ecchymosis in flank area) Cholera: Rice-watery stool: Typhoid fever: Rose spots in abdomen: Meningitis: Kernig's sign and Brudzinski's sign: Cholecystitis: Murphy's sign (pain on deep inspiration when inflamed gallbladder is.
Has 6 years experience. Nov 4, 2010. Babinski's reflex, Battle's sign, Brudzinski's sign, Chvostek's sign, Cullen's sign, Cushing's triad, DeMusset's sign, Duroziez's sign, Fremitus, Grey Turner's Sign, Hill's sign, Homan's sign, Janway lesions, Kehr's sign, Kerley's B lines, Kernig's sign, McBurney's point, Muller's sign, Murphy's sign, Psoas. Cullen's and Grey-Turner's Sign (seen with SEVERE cases of acute pancreatitis) What causes Cullen's and Grey-Turner's Sign? They represent retroperitoneal bleeding from the leakage of digestive enzymes into the surrounding tissues which is causing bleeding and it is leaking down in to the flanks and umbilicus
Cullen's sign and Grey Turner's sign. Thomas Cullen (1868-1953), a gynaecologist at Johns Hopkins, Balti-more, described a periumbilical bluish discolouration in a case of ruptured ectopic pregnancy in 1922. George Grey Turner (1877-1951), a surgeon from Newcastl ment. Even with typical symptoms and signs, ruptured AAA may be misdiagnosed as renal colic, perforated viscus, diverticulitis, E-7 Figure 1. Bruising around the umbilicus (Cullen's sign, blue arrow) and the flanks (Grey Turner's sign, red arrow) Figure 2. Dilated abdominal aorta (6 cm, red double arrow) with intramu 62988009: English: Abdom wall discolor, L flank, Abdom wall discolour, L flank, Gray Turner's sign, flank ecchymosis, Grey Turner's sign (physical finding), abdomen Grey Turner's sign (flank ecchymosis), ecchymosis of flank (physical finding), ecchymosis of flank, Grey Turner sign, gray turner's sign, grey sign turner, grey sign turners, grey turner's sign, grey turner sign, turner's sign. Grey Turner sign. This 40-year-old woman complained of worsening epigastric pain of five days' duration. On examination, she had hypotension, a board-like abdomen, and extensive ecchymoses over.
Grey-Turner's sign refers to bruising of the area between the last rib and top of the hip and is a sign of retroperitoneal hemorrhage. Cullen's sign is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus. Causes include acute pancreatitis, ruptured ectopic, aortic rupture, and coagulopathies Cullen's sign (bruising near umbilicus) is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus. Grey Turner's sign (flank bruising) refers to bruising of the flanks, the part of the body between the last rib and the top of the hip Ecchymosis involving the flanks (Grey Turner sign) or the umbilicus (Cullen sign) indicates retroperitoneal hemorrhage, but this is usually delayed for several hours to days. Visual inspection for abdominal distention, which may be due to pneumoperitoneum, gastric dilatation secondary to assisted ventilation or swallowing of air, or ileus.
Cullen's sign and the analogous Grey Turner's sign of the flank are seen in only ca. 1% of patients with pancreatitis but are associated with up to 40% mortality. Dr. med. Klaus Dirks. groin include Cullen sign (periumbilical discolor-ation), Grey Turner sign (lateral abdominal wall), Stabler sign (inguinal pubic region), seatbelt sign and the Blue scrotum of Bryant.1 Fox sign indicates lateral thigh discoloration. These signs are usually indicative of a surgical or obstetric emergency suc
Signs of liver disease (tortuous abdominal vessels or jaundice) or pancreatic hemorrhage (Grey Turner and Cullen signs) may be evident. See images below. A person with jaundice due to hepatic failure. View Media Gallery. Grey Turner sign. This 40-year-old woman complained of worsening epigastric pain of five days' duration The Grey Turner sign refers to the clinical finding of atraumatic flank ecchymosis, which is occasionally associated with retroperitoneal hemorrhage, classically due to hemorrhagic pancreatitis . It is thought to occur when blood extravasates from the posterior pararenal space and crosses through the transversalis fascia, emerging subcutaneously after dissecting along the lateral aspect of the. SIGNS / SYMPTOMS. Epigastric or periumbilical abdominal pain that radiates to the back. Ecchymosis in the periumbilical region (Cullen sign) or the flank (Grey Turner sign) may be present in severe pancreatitis A) Cullen sign, necrotizing pancreatitis. It can sometimes be seen in other emergent diagnosis as well, specifically different types of internal hemorrhage. If you can just simply think of the U in Cullen to remember the umbilicus Grey Turner sign is similar but the area differs. Ecchymosis is seen around the flank areas
abdominal and inguinal palpation, rigidity, tenderness • abdominal auscultation, bowel sounds • abdominal percussion • asterixis • Cullen sign • fluid thrill or wave • Grey Turner sign • Murphy sign • peritoneal signs • puddle maneuver • shifting dullnes Cullen, T. S.: Bluish Discoloration of the Umbilicus as a Diagnostic Sign Where Ruptured Extra-Uterine Pregnancy Exists, from Contributions to Medical and Biological Research, dedicated to Sir William Osler, in Honor of His Seventieth Birthday, July 12, 1919, by His Pupils and Co-Workers Grey Turner sign. Ecchymosis on the lateral abdominal walls between the twelfth rib and top of the hip; caused by retroperitoneal bleeding from pancreatic hemorrhage, blunt abdominal trauma. sign 1. Maths logic a. any symbol indicating an operation b. the positivity or negativity of a number, quantity, or expression 2. an indication, such as a scent or spoor, of the presence of an animal 3. Med any objective evidence of the presence of a disease or disorder 4. Astrology See sign of the zodiac Collins Discovery Encyclopedia, 1st edition. A positive Grey Turner test occurs when a patient has bruising of flanks (last rib to top of hip), which indicates a retroperitoneal hemorrhage. Both Cullen and Grey Turner signs are used to indicate/predict acute pancreatitis, when these signs are present one has a high rate of mortality (37%) SIGN, contracts, evidence. A token of anything; a note or token given without words. 2. Contracts are express or implied. The express are manifested viva voce, or by writing; the implied are shown by silence, by acts, or by signs. 3. Among all nations find and at all times, certain signs have been considered as proof of assent or dissent; for.